Table 2.
Blood cell profile and white blood cell classification in male offspring received prenatal dexamethasone or/with a postnatal high-fat diet at postnatal day 120 and D 180. The result is presented as mean ± S.E.M. (n = 6 for each group). Only significant p-values as compared with the VEH group are listed here.
| D120 | ||||
|---|---|---|---|---|
| Group | VEH | DEX | VHF | DHF |
| WBC (103/μL) | 12.16 ± 2.49 | 10.57 ± 1.56 | 10.57 ± 0.94 | 8.58 ± 0.89 |
| RBC (106/μL) | 9.26 ± 0.24 | 9.45 ± 0.26 | 9.14 ± 0.21 | 9.07 ± 0.17 |
| HGB (g/dL) | 16.38 ± 0.44 | 15.44 ± 0.45 | 15.98 ± 0.32 | 15.33 ± 0.23 |
| PLT (103/μL) | 1036.50 ± 51.86 | 1075.60 ± 191.95 | 1100.67 ± 70.79 | 935.00 ± 51.41 |
| Neutrophil (%) | 12.00 ± 0.24 | 17.34 ± 1.67 (p = 0.014) | 22.33 ± 3.45 (p = 0.018) | 19.08 ± 2.74 (p = 0.033) |
| Lymphocyte (%) | 84.05 ± 0.35 | 78.66 ± 1.82 (p = 0.014) | 73.78 ± 3.57 (p = 0.028) | 76.32 ± 3.14 |
| Monocyte (%) | 2.33 ± 0.30 | 2.68 ± 0.47 | 2.85 ± 0.37 | 3.65 ± 0.47 (p = 0.049) |
| Eosinophil (%) | 1.58 ± 0.41 | 1.28 ± 0.45 | 1.00 ± 0.18 | 0.92 ± 0.18 |
| Basophil (%) | 0.05 ± 0.03 | 0.04 ± 0.02 | 0.03 ± 0.02 | 0.03 ± 0.03 |
| CD4+ (%) | 62.08 ± 3.77 | 60.02 ± 1.99 | 58.97 ± 2.54 | 55.72 ± 1.71 |
| CD8a+ (%) | 36.06 ± 3.72 | 37.37 ± 2.53 | 36.68 ± 2.54 | 40.93 ± 1.74 |
| CD4+CD8a+ (%) | 1.50 ± 0.21 | 2.20 ± 0.67 | 3.65 ± 0.85 (p = 0.042) | 2.72 ± 0.69 |
| CD4−CD8a− (%) | 0.32 ± 0.04 | 0.40 ± 0.08 | 0.67 ± 0.13 (p = 0.014) | 0.62 ± 0.06 (p = 0.032) |
| CD45RA (%) | 2.40 ± 0.65 | 1.15 ± 0.40 | 1.28 ± 0.39 | 1.68 ± 0.70 |
| D180 | ||||
| Group | VEH | DEX | VHF | DHF |
| WBC (103/μL) | 11.55 ± 1.98 | 11.79 ± 1.33 | 7.82 ± 0.86 | 7.06 ± 0.76 (p = 0.030) |
| RBC (106/μL) | 9.16 ± 0.31 | 9.52 ± 0.33 | 9.04 ± 0.11 | 8.92 ± 0.17 |
| HGB (g/dL) | 15.35 ± 0.51 | 16.68 ± 0.63 | 15.07 ± 0.18 | 16.30 ± 0.30 |
| PLT (103/μL) | 1070.75 ± 158.53 | 1215.40 ± 112.81 | 1137.33 ± 51.84 | 1217.50 ± 20.33 |
| Neutrophil (%) | 19.35 ± 3.44 | 18.43 ± 0.77 | 20.75 ± 2.92 | 19.27 ± 2.22 |
| Lymphocyte (%) | 75.88 ± 3.54 | 77.83 ± 1.31 | 61.00 ± 10.85 | 76.70 ± 2.33 |
| Monocyte (%) | 3.30 ± 0.46 | 2.83 ± 0.34 | 4.67 ± 0.54 | 3.25 ± 0.38 |
| Eosinophil (%) | 1.45 ± 0.44 | 0.90 ± 0.23 | 1.12 ± 0.12 | 0.78 ± 0.23 |
| Basophil (%) | 0.03 ± 0.03 | 0.04 ± 0.02 | 0.02 ± 0.02 | 0.00 ± 0.00 |
| CD4+ (%) | 66.03 ± 2.25 | 66.06 ± 2.04 | 58.75 ± 2.71 | 62.83 ± 1.50 |
| CD8a+ (%) | 31.80 ± 1.98 | 32.60 ± 2.08 | 39.78 ± 2.58 | 35.60 ± 1.58 |
| CD4+CD8a+ (%) | 0.73 ± 0.07 | 0.64 ± 0.07 | 0.60 ± 0.09 | 0.57 ± 0.08 |
| CD4−CD8a− (%) | 1.43 ± 0.42 | 0.74 ± 0.05 | 0.88 ± 0.07 | 0.98 ± 0.19 |
| CD45RA (%) | 1.28 ± 0.23 | 2.22 ± 0.67 | 1.03 ± 0.18 | 1.22 ± 0.28 |