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. 2016 Sep 24;17(10):1624. doi: 10.3390/ijms17101624

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© 2016 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effect of dietary fat on plasma biochemistry. Wild-type (Pparα^+/+) and total Pparα knockout (Pparα^−/−) mice were fed ad libitum or fasted for 24 h and then euthanized at ZT14. Quantification of plasma glucose (a); free fatty acids (b); plasma triglycerides (c); LDL cholesterol (d); HDL cholesterol (e); total cholesterol (f); alanine transaminase (ALT) (g); and aspartate transaminase AST (h) activity is given as mean ± SEM. n = 6–8 mice/genotype/diet. * Significant genotype effect, ^# significant effect of diet composition, ^§ significant effect of fasting. *, ^#, ^§ p ≤ 0.01. **, ^##, ^§§ p ≤ 0.001.

Effect of dietary fat on plasma biochemistry. Wild-type (Pparα^+/+) and total Pparα knockout (Pparα^−/−) mice were fed ad libitum or fasted for 24 h and then euthanized at ZT14. Quantification of plasma glucose (a); free fatty acids (b); plasma triglycerides (c); LDL cholesterol (d); HDL cholesterol (e); total cholesterol (f); alanine transaminase (ALT) (g); and aspartate transaminase AST (h) activity is given as mean ± SEM. n = 6–8 mice/genotype/diet. * Significant genotype effect, ^# significant effect of diet composition, ^§ significant effect of fasting. *, ^#, ^§ p ≤ 0.01. **, ^##, ^§§ p ≤ 0.001.