Figure 4.

Schematic depiction of a system in which the dimer lacks a clear hydrophobic core while each monomer retains a well-defined core. Elimination of residues involved in complexation (right-hand image) leads to better accordance with the model when considering the dimer as a whole. Blue and pink lines: distributions in monomers, gray line: distribution in dimer. (A) Status of the individual monomers (blue and pink) versus the resultant distribution in dimer (gray); (B) Removal of the interface (black bar) changes the status of the dimer—Distribution appears accordant versus the expected one.