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. 2016 Oct 20;17(10):1753. doi: 10.3390/ijms17101753

Figure 7.

Figure 7

Melanin biosynthesis from dopamine. Tyrosinase or other oxidative enzymes/reactants will convert dopamine to dopaminequinone. Intramolecular cyclization to leucochrome and further oxidation of the leucochrome produces the dopaminechrome. Dopaminechrome is converted to DHI by isomerization reaction. Further oxidation of DHI to its quinonoid products and their eventual polymerization leads to dopamine melanins, which is DHI melanin.