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. 2016 Oct 20;17(10):1753. doi: 10.3390/ijms17101753

Figure 10.

Figure 10

Thiol addition to dopaquinone. Thiols such as cysteine add on to dopaquinone not by conventional Michael-1,4-addition reaction. They react by an unconventional 1,6-addition, producing 5-S-cysteinyl dopa as the major product and 2-S-cysteinyldopa as the minor product. In addition 2,5-dicysteinyldopa is also formed to a certain extent. RSH—Cysteine.