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. 2016 Oct 21;17(10):1762. doi: 10.3390/ijms17101762

Table 1.

Effects of 4-Methylbenzylidene Camphor (4-MBC), propylparaben (PP) and triclocarban (TCC) exposures in Danio rerio. Controls and solvent controls were grouped. Significantly different results from controls (p < 0.05) are marked with a symbol (*). Data are expressed as mean ± SE (n = 16 for 4-MBC controls; n = 32 for propylparaben and triclocarban controls; n = 8 for exposed groups).

Compound Endpoints
Treatment (µg/L) Mortalitiy Rate Hatching Rate Abnormal Cellular Growth 75%-Epiboly Head Abnormalities Eyes Abnormalities Yolk-sac Abnormalities Tail Abnormalities Pericardial Edema Heart Rate Total Abnormalities Abnormal Muscular Contractions
4-MBC Controls 1.88 ± 1.0 95.0 ± 1.58 1.25 ± 0.85 90.0 ± 6.26 1.04 ± 1.04 1.04 ± 1.04 1.04 ± 1.04 2.08 ± 1.42 1.04 ± 1.04 126.75 ± 4.46 2.08 ± 1.42 0.0 ± 0.0
5 7.5 ± 4.12 87.5 ± 3.66 7.5 ± 4.12 91.25 ± 3.98 4.17 ± 2.72 4.17 ± 2.72 4.17 ± 2.72 6.25 ± 3.05 2.08 ± 2.08 123.5 ± 3.58 6.25 ± 3.05 0.0 ± 0.0
50 6.25 ± 2.63 92.5 ± 3.13 3.75 ± 2.63 95.0 ± 2.67 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 6.25 ± 4.38 0.0 ± 0.0 120.0 ± 4.21 6.25 ± 4.38 0.0 ± 0.0
500 5.0 ± 2.67 81.25 ± 4.79 3.75 ± 1.82 92.5 ± 3.13 4.17 ± 2.72 4.17 ± 2.72 4.17 ± 2.72 10.42 ± 3.05 2.08 ± 2.08 121.0 ± 3.53 10.42 ± 3.05 35.42 ± 11.55 *
5000 2.5 ± 1.64 38.75 ± 7.66 * 1.25 ± 1.25 92.5 ± 4.91 4.17 ± 2.72 2.08 ± 2.08 2.08 ± 2.08 8.33 ± 4.45 2.08 ± 2.08 95.0 ± 3.0 * 10.42 ± 4.38 85.42 ± 3.78 *
PP Controls 3.13 ± 0.95 92.19 ± 1.89 1.56 ± 0.65 97.81 ± 0.74 1.56 ± 0.87 1.56 ± 0.87 1.56 ± 0.87 3.13 ± 1.17 2.08 ± 0.99 143.0 ± 2.02 3.13 ± 1.17
10 2.5 ± 1.64 87.5 ± 4.11 1.25 ± 1.25 96.25 ± 1.83 2.08 ± 2.08 2.08 ± 2.08 2.08 ± 2.08 2.08 ± 2.08 2.08 ± 2.08 144 ± 5.01 2.08 ± 2.08
100 1.25 ± 1.25 90.0 ± 3.78 1.25 ± 1.25 98.75 ± 1.25 0.0 ± 0.0 0.0 ± 0.0 2.08 ± 2.08 0.0 ± 0.0 2.08 ± 2.08 146.0 ± 3.38 2.08 ± 2.08
1000 4.37 ± 1.57 85.68 ± 5.91 1.25 ± 0.85 94.49 ± 1.76 3.13 ± 1.68 2.08 ± 1.42 2.08 ± 1.42 2.08 ± 1.42 2.08 ± 1.42 139.75 ± 3.36 4.17 ± 1.86
3500 3.75 ± 1.83 66.25 ± 8.22 1.25 ± 1.25 96.25 ± 1.82 95.83 ± 2.73 * 89.58 ± 5.4 * 58.33 ± 7.04 * 91.67 ± 3.15 * 91.67 ± 4.45 * 124.5 ± 6.16 * 100 ± 0.0 *
6000 1.25 ± 1.25 18.75 ± 3.98 * 1.25 ± 1.25 91.25 ± 3.98 100 ± 0.0 * 95.83 ± 4.17 * 83.33 ± 8.33 * 93.75 ± 6.25 * 100 ± 0.0 * 67.5 ± 7.98 * 100 ± 0.0 *
8500 21.25 ± 7.89 2.5 ± 2.5 * 1.25 ± 1.25 87.5 ± 4.53 * 100 ± 0.0 * 100 ± 0.0 * 100 ± 0.0 * 100 ± 0.0 * 100 ± 0.0 * 70.29 ± 6.47 * 100 ± 0.0 *
10,000 100 ± 0.0 * 0.0 ± 0.0 * 0.0 ± 0.0 87.5 ± 3.13 *
TCC Controls 2.19 ± 0.87 96.88 ± 0.95 1.56 ± 0.79 97.81 ± 0.87 0.52 ± 0.52 0.52 ± 0.52 0.0 ± 0.0 0.0 ± 0.0 1.58 ± 0.88 130.5 ± 3.53 0.52 ± 0.52
10 1.25 ± 1.25 98.75 ± 1.25 1.25 ± 1.25 98.75 ± 1.25 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 4.25 ± 2.78 118.5 ± 4.07 0.0 ± 0.0
100 6.25 ± 1.8 91.11 ± 2.26 1.68 ± 1.01 93.61 ± 2.08 2.08 ± 1.42 2.08 ± 1.42 2.08 ± 1.42 3.12 ± 1.68 4.23 ± 1.89 128.0 ± 4.29 3.13 ± 1.68
350 75.0 ± 12.81 * 91.25 ± 4.79 0.0 ± 0.0 97.5 ± 1.64 5.56 ± 5.56 0.0 ± 0.0 0.0 ± 0.0 33.33 ± 33.33 0.0 ± 0.0 72.0 ± 48.0 33.33 ± 33.33
600 95.0 ± 5.0 * 92.5 ± 3.66 1.25 ± 1.25 97.5 ± 1.64 0.0 ± 0.0 0.0 ± 0.0 0.0 ± 0.0 16.67 ± 16.67 0.0 ± 0.0 16.67 ± 16.67
850 100 ± 0.0 * 93.75 ± 2.63 1.25 ± 1.25 98.75 ± 1.25
1000 100 ± 0.0 * 95.0 ± 2.76 0.0 ± 0.0 100 ± 00
10,000 100 ± 0.0 * 83.75 ± 5.32 0.0 ± 0.0 98.75 ± 1.25