Table 1.
Clinical data on the first day of ampicillin exposure
| Infants with seizure | All infants N=131,723 |
|||
|---|---|---|---|---|
| Yes N=780 |
No N=130,943 |
|||
| Gestational age at birth (weeks) | 37 (33, 39) | 35 (32, 38) | 35 (32, 38) | |
| Birth weight (g) | 2833 (1815, 3343) | 2390 (1692, 3100) | 2394 (1692, 3102) | |
| Postmenstrual age (weeks) | 37 (33, 39) | 35 (32, 38) | 35 (32, 38) | |
| Postnatal/gestational age, N (%) | ||||
| ≤7 days & ≤34 weeks | 233 (30) | 60,004 (46) | 60,237 (46) | |
| ≤7 days & >34 weeks | 529 (68) | 68,691 (52) | 69,220 (53) | |
| 8–25 days & ≤34 weeks | 10 (1) | 1538 (1) | 1548 (1) | |
| 8–25 days & >34 weeks | 8 (1) | 710 (1) | 718 (<1) | |
| Serum creatinine (mg/dL) | 0.9 (0.7, 1.2) | 0.8 (0.7, 0.9) | 0.8 (0.7, 0.9) | |
| Positive blood culture, N (%) | 51 (7) | 1927 (2) | 1978 (2) | |
| Positive CSF culture, N (%) | 17 (2) | 88 (<1) | 105 (<1) | |
| Positive blood or CSF culture, N (%) |
52 (7) | 1962 (2) | 2014 (2) | |
Data presented as median (25th, 75th percentile) unless indicated. CSF=cerebrospinal fluid.