Table 2.

Comparison of demographic and clinical characteristics between infants with and without cerebral oxygen desaturation (rSO₂c) events 20 % or more from baseline during surgery. Data are shown as median (min-max) or proportions (n (%))

Demographic and preanesthetic parameters	Normal group (n = 35)	Desaturation group (n = 8)	p
Age (days)	8 (0–70)	2 (0–39)	0.09
Gestation (weeks)	38 (33–41)	35.5 (25–38)	0.007
Weight (kg)	3.4 (1.8–5.0)	2.81 (0.8–3.8)	0.04
Preoperative MAPa (mmHg)	52 (36–84)	44 (33–64)	0.2
Hypotensionb (n (%))	2 (5.7 %)	0 (0 %)	0.5
Preoperative hemoglobin (g∙l−1)	165 (82–231)	147.5 (98–195)	0.13
Preoperative blood lactate (mmol/l)	2.1 (0.9–5.8)	2.3 (1.7–4.3)	0.27
Preoperative mechanical ventilation (n (%))	2 (5.7 %)	5 (62.5 %)	0.000
Baseline rSO2c (%)	83.5 (70–95)	87.5 (65.5-95)	0.8
Anesthetic parametersc
Intraoperative SpO2 (%)	97.5 (91.1–99.4)	96.6 (90.5–99.9)	0.4
Intraoperative heart rate (beats per min)	143 (115.6–166.9)	149.7 (129.2–164.7)	0.4
Expired fraction of sevoflurane (%)	1.85 (0.72–2.7)	1.79 (0.5–2.6)	0.3
etCO2 during anesthesia (mmHg)	34.9 (20.9–50.7)	35.1 (21.1–49)	0.9
Intraoperative rectal temperature (°C)	37 (36.1–38.2)	36.9 (36–37.5)	0.2
Intraoperative MAP (mmHg)	50.0 (25.1–62.1)	39.4 (30.3–57.2)	0.06
MAPminrSO2c (mmHg)d	47 (22–76)	43 (23–56)	0.16
Vasoactive agents (n (%))	4 (11.3 %)	4 (50 %)	0.01
Red blood cell transfusion (n (%))	2 (5.7 %)	4 (50 %)	0.001
Postanesthesia parameters
Postoperative blood lactate level (mmol/l)	1.45 (1.1–2.2)	1.5 (1.0–3.0)	0.83
Hemoglobin change during surgery (g∙l−1)	−21 ((−44)–18)	−35 ((−43)–23)	0.16

^amean arterial blood pressure

^bhypotension was defined as MAP less than gestational age in weeks for premature newborns and less than 38 mmHg for term newborns and infants [8, 12]

^caverage intraoperative value of heart rate, SpO₂, etCO₂, expired fraction of sevoflurane, rectal temperature, MAP was calculated for each patient

^dmean arterial blood pressure corresponding to minimal rSO₂c during anesthesia