Table 2.
Pathologic Response | Ryan Tumor Regression Grade | No. of Patients (%) |
---|---|---|
No viable cancer cells or single cells/small groups of cancer cells | 1 | 14 (28) |
Residual cancer outgrown by fibrosis | 2 | 22 (44) |
Significant fibrosis outgrown by cancer or no fibrosis with extensive residual cancer | 3 | 14 (28) |
Tumor Regression Grade (TRG) based upon patient pre-operative and post-operative TNM stages using the surgical histopathology. Patients with a score of 1 were considered to have had a complete response (28%), patients with a 2 to have had a partial response (44%), and patients with a score of 3 to have had no response (28%).