Table 2.
Metabolic syndrome components and cardiovascular disease endpoints in all women
| Sexual Activity | Sexual Desire | Sexual Satisfaction | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Yes N=148 |
No N=228 |
P value | Yes N=87 |
No N=283 |
P value | Yes N=199 |
No N=56 |
P value | |
| Age, y | 67.9 ± 8.0 | 76.2 ± 8.8 | <0.0001 | 69.3 ± 8.5 | 74.0 ± 9.4 | <0.0001 | 70.5 ± 8.6 | 69.9 ± 9.6 | 0.6605 |
| Years post menopause | 21.7 ± 11.0 | 29.7 ± 12.4 | <0.0001 | 23.6 ± 11.8 | 27.5 ± 12.6 | 0.0193 | 23.6 ± 10.9 | 22.4 ± 13.3 | 0.5592 |
| Marital Status | <0.0001 | 0.0016 | 0.1348 | ||||||
| Live w/spouse/partner | 117 (79.1%) | 109 (47.8%) | 65 (74.7%) | 156 (55.1%) | 151 (75.9%) | 38 (67.8%) | |||
| Widowed | 17 (11.5%) | 89 (39.0%) | 12 (13.8%) | 93 (32.9%) | 31 (15.6%) | 8 (14.3%) | |||
| Other | 14 (9.4%) | 30 (13.2%) | 10 (11.5%) | 34 (12.0%) | 17 (8.5%) | 10 (17.9%) | |||
| BMI, kg/m2 | 25.6 ± 4.4 | 26.0 ± 4.7 | 0.3958 | 25.9 ± 5.1 | 25.8 ± 4.4 | 0.8761 | 26.0 ± 4.7 | 26.9 ± 5.0 | 0.1746 |
| Waist, cm | 81.5 ± 10.5 | 84.5 ± 11.8 | 0.0125 | 81.5 ± 12.7 | 83.8 ± 11.0 | 0.0946 | 83.0 ± 11.3 | 85.8 ± 11.4 | 0.1032 |
| HDL, mg/dL | 67.6 ± 16.8 | 67.4 ± 17.5 | 0.9047 | 69.2 ± 16.8 | 67.3 ± 17.3 | 0.3527 | 67.8 ± 17.1 | 65.6 ± 17.8 | 0.4071 |
| Triglycerides, mg/dL | 132.0 (94.0) | 135.5 (92.0) | 0.5316 | 121.0 (73.0) | 137.0 (95.0) | 0.0141 | 131.0 (92.0) | 135.5 (105.5) | 0.3242 |
| Diabetes | 13 (8.8%) | 45 (19.7%) | 0.0041 | 10 (11.5%) | 48 (17.0%) | 0.2200 | 29 (14.6%) | 6 (10.7%) | 0.4585 |
| Hypertension | 92 (62.2%) | 194 (85.1%) | <0.0001 | 62 (71.3%) | 218 (77.0%) | 0.2728 | 141 (70.9%) | 42 (75.0%) | 0.5426 |
| IGT | 83 (56.1%) | 143 (62.7%) | 0.1991 | 43 (49.4%) | 179 (63.2%) | 0.0213 | 113 (56.8%) | 35 (62.5%) | 0.4438 |
| DM + IGT | 96 (64.9%) | 188 (82.5%) | 0.0001 | 53 (60.9%) | 227 (80.2%) | 0.0002 | 142 (71.4%) | 41 (73.2%) | 0.7850 |
| Metabolic Syndrome | 46 (31.1%) | 110 (48.3%) | 0.0010 | 22 (25.3%) | 129 (45.6%) | 0.0008 | 74 (37.2%) | 24 (42.9%) | 0.4409 |
| Number of MetS - components | <0.0001 | 0.0002 | 0.0192 | ||||||
| 0 | 12 (8.1%) | 5 (2.2%) | 6 (6.9%) | 11 (3.9%) | 13 (6.5%) | 0 (0.0%) | |||
| 1 | 46 (31.1%) | 21 (9.2%) | 29 (33.3%) | 37(13.1%) | 38 (19.1%) | 16 (28.6%) | |||
| 2 | 44 (29.7%) | 92 (40.3%) | 30 (34.5%) | 106 (37.5%) | 74 (37.2%) | 16 (28.6%) | |||
| 3 | 23 (15.5%) | 62 (27.2%) | 11 (12.6%) | 71 (25.1%) | 43 (21.6%) | 8 (14.3%) | |||
| 4 | 14 (9.5%) | 40 (17.6%) | 7 (8.1%) | 46 (16.3%) | 26 (13.1%) | 11 (19.6%) | |||
| 5 | 9 (6.1%) | 8 (3.5%) | 4 (4.6%) | 12 (4.2%) | 5 (2.5%) | 5 (8.9%) | |||
| CVD Endpoints | |||||||||
| Heart attack | 3 (2.1%) | 15 (6.9%) | 0.0403 | 1 (1.2%) | 16 (5.9%) | 0.0856 | 7 (3.6%) | 2 (3.6%) | 1.0000 |
| CABG | 3 (2.1%) | 17 (7.9%) | 0.0184 | 2 (2.4%) | 17 (6.3%) | 0.2665 | 11 (5.6%) | 0 (0.0%) | 0.1299 |
| Heart failure | 1 (0.7%) | 6 (2.8%) | 0.2502 | 1 (1.2%) | 5 (1.9%) | 1.0000 | 3 (1.6%) | 0 (0.0%) | 1.0000 |
| Angina | 2 (1.4%) | 15 (6.9%) | 0.0149 | 1 (1.2%) | 15 (5.5%) | 0.1317 | 7 (3.6%) | 1 (1.8%) | 0.6879 |
| Poor arterial circulation | 8 (5.6%) | 20 (9.5%) | 0.1742 | 5 (5.9%) | 23 (8.7%) | 0.4035 | 14 (7.2%) | 2 (3.6%) | 0.5353 |
| Stroke | 3 (2.1%) | 3 (1.4%) | 0.6868 | 0 (0.0%) | 5 (1.9%) | 0.3434 | 3 (1.6%) | 0 (0.0%) | 1.0000 |
| TIA | 6 (4.2%) | 17 (7.8%) | 0.1656 | 4 (4.7%) | 18 (6.6%) | 0.5035 | 9 (4.6%) | 3 (5.4%) | 0.7340 |
Mean ± standard deviation is presented for normally distributed continuous variables and associated p values are from t test. Median (interquartile range) for non-normally distributed variables with p values from Wilcoxon-Mann-Whitney test. Categorical variables are shown as N (%) and a chi-square or Fisher’s test was performed. Definitions: Diabetes => HbA1c ≥ 6.5 or history or meds; Hypertension => SBP ≥ 130 or DBP ≥ 85 or history or meds; IGT => 5.7 ≤ HbA1c < 6.5 and No Diabetes (as defined above); IGT + DM => Diabetes (as defined above) or IGT (as defined above).