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. 2016 Sep 26;18(4):514–531. doi: 10.22074/cellj.2016.4718

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Fig.3 — Selection of central nodes for pathway enrichment analysis can detect critical signaling pathways. In the enriched protein-protein interaction (PPI) networks, 62 genes for 24 hours treatment network and 60 genes for 48 hours treatment network were chosen as nodes with high cen trality. These central nodes are related to 29 and 49 highly c onnected pathways in A. 24 hours and B. 48 hours, respectively. Pathways with adjusted P≤0.05 are shown. Color represents the gene ontology (GO) term level.