Table 8.
Fetal and neonatal gemistocytic astrocytoma (n = 3)
| Female/male | 2/1 |
| Fetusesa | 3 |
| Neonatesb | 0 |
| Gestation (weeks) | 35, range 32–40 |
| Birth weight (g) | 3523c |
| Maternal history | |
| Maternal age (years) | 29, range 19–36 |
| Gravida | G1, G3 |
| Delivery | |
| Vaginal | 0 |
| Cesarian section | 3 |
| Initial findings | |
| Macrocephalus | 3 |
| Hydrocephalus | 3 |
| Intracranial mass discovered on imaging | 2 |
| Intracranial hemorrhage | 2 |
| Bulging anterior fontanel | 1 |
| Seizures | 1 |
| Dystocia | 1 |
| Irritability | 1 |
| Vomiting | 1 |
| Location | |
| Cerebral hemisphere, occipital lobe | 1 |
| Cerebral hemispheres replaced by tumor | 1 |
| Tumor filled one half of intracranial cavity | 1 |
| Tumor characteristics | |
| Brain weight (g) | 654c |
| Tumor weight (g) | |
| Tumor greatest dimension (cm) | |
| Treatment and survival | |
| Patients treated | 1 (1/3) |
| Patients not treated | 2 (0/3) |
| Survival with surgical resection + chemotherapy | 1 (1/1)d |
| Outcome | |
| Fetal | 1/3 |
| Patients treated survived | 1/1 |
| Patients not treated survived | 0/2 |
| Overall survival | 1/3 = 33 % |
Cases selected from the literature
aTumor discovered before birth or on the first day of life
bTumor discovered during the first 2 months of life
cGiven for one patient only
dCombination chemotherapy using cisplatinum and vincristine. Patient had a recurrence at age 10 months