Table 2.

Characteristics of included studies investigating 11C-Methionine

Study First author	Year	No. of patients		Study population	Dose (MBq)	CT	Time (min)
		Total	pHPT + surgery
Braeuning	2015	18	12	Neg/disc imaging	600	yes	20
Hayakawa	2015	23	15	Mixed	441–906	yes	15–34
Chicklore	2014	43	15	Mixed	740	yes	10
Martinez	2014	14	14	Mixed	740	yes	10 and 40
Weber	2013	102	102	Mixed	?	yes	20
Chun	2013	16	8	Neg/disc imaging	370–444	yes	30–40
Schalin	2012	21	21	Previous surgery	440	yes	20
Oksuz	2011	8	8	Mixed	700	4/4	15
Weber	2010	33	33	Mixed	?	yes	20
Herrmann	2009	41	9	Mixed	430	no	15–20
Tang	2008	30	22	Mixed	555	yes	20
Beggs	2005	51	29	Neg/disc imaging	619	no	15
Otto	2004	30	14	Mixed	900–1100	no	10
Sundin	1996	34	25	Previous surgerya	750	no	direct

pHPT primary hyperparathyroidism, Neg negative, Disc discordant

^aPrevious surgery in 25/34 patients included in the study