Table 3.
Characteristics of studies investigating PET tracers other than 11C-Methionine
| Study First author |
Tracer | Year | No. of patients | Dose (MBq) | CT | Time (min) | Sens (%) | PPV (%) | |
|---|---|---|---|---|---|---|---|---|---|
| Total | pHPT + surgery | ||||||||
| Kluijfhout | 18F-FCH | 2015 | 5 | 5 | 2 MBq/kg | yes | direct | 80 | 100 |
| Michaud | 18F-FCH | 2015 | 17 | 11 | 3 MBq/kg | yes | direct | 94 | 91 |
| Lezaic | 18F-FCH | 2015 | 43 | 43 | 100 | yes | 5,60,120 | 95 | 97 |
| Orevi | 11C-CH | 2014 | 40 | ? | 370 | yes | direct | ? | ? |
| Lange-Nolde | 18F-DOPA | 2006 | 8 | 8 | 185–300 | no | 90 | – | – |
| Chicklore | 18F-FDG | 2014 | 43 | 15 | 400 | yes | 90 | 27 | 100 |
| Neumann | 18F-FDG | 1997 | 20 | 20 | 185–370 | no | 45 | 62 | 62 |
| Neumann | 18F-FDG | 1996 | 21 | 21 | 185–370 | no | 45 | 86 | 86 |
| Melon | 18F-FDG | 1995 | 7 | 7 | 370 | no | 50 | 22 | 100 |
| Sisson | 18F-FDG | 1994 | 8 | 8 | 370 | no | ? | 0 | – |
| Neumann | 18F-FDG | 1994 | 17 | 17 | 185–370 | no | 45 | 94 | 85 |
pHPT primary hyperparathyroidism, Sens sensitivity, PPV positive predictive value