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. Author manuscript; available in PMC: 2016 Oct 30.
Published in final edited form as: Microbiol Spectr. 2013 Dec;1(2):10.1128/microbiolspec.AID-0002-2012. doi: 10.1128/microbiolspec.AID-0002-2012

TABLE 2.

List of MAbs generated against SEB toxins

Source Ab(s) Affinity
unit(s)
In vitro model(s) In vivo
model(s)
Reference
Murine lFD7, 2DA3 and 2HA10, 2EG5 and 2GD9 BALB/c splenocytes 72
Murine B334, B327, B87, 2B33 nM Mouse Vβ8.2 + T cell (KS-6.1) 64
Murine MAb5 (anti-TSST MAb) Human PBMCs 63
Chicken IgY BALB/c Rhesus
monkeys
66
Murine phage display Soluble SEB-ScFv nM 73
Chimeric Ch82M and Ch63 pM HLA-DR3 mouse splenocytes 67
Human 10 Fab and 4 full-length MAbs nM Human PBMCs BALB/c 69
Human Human MAb79G9, human MAb154 pM–nM Human PBMCs BALB/c 70
Murine 20B1, 14G8, 6D3, 4C7 Human T cells BALB/c,
HLA-DR3
21
Chimeric + lovastatin Ch82M and Ch63 with lovastatin BALB/c mouse splenocytes HLA-DR3 68
Murine 3F3 (anti-SEAand -SEB) 74
Synthetic human MAb IgG 075, IgG 079, IgG 079-P, IgG 119,
 IgG 120, IgG 121
nM Human PBMCs BALB/c 71