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Noise exposure results in significantly elevated thresholds for Alport mice relative to wild type mice. Mice were exposed to noise (8-17 kHz, 106 dB SPL) for 10 hrs. Hearing was assessed using the ABR immediately post-noise exposure (panel A) and again at 5 days post-noise exposure (panel B). Asterisks denote frequencies that contributed to the statistically significant differences noted overall between the wild type and Alport mice(P<0.05).
