Table 3.
Table of parameter perturbation and its effect on numerical outcomes in cellular density and chemical concentration.
| Variable | EP | HP | MP | MN | HN |
|---|---|---|---|---|---|
| CT | β13 = 20 | β13 = 15 | λF = 0.3 | β13 = 5 | β13 = 1 |
| λF = 0.1 | κ1 = 1 | λM = 0.9 | λM = 0.1 | ||
| λM = 0.3 | λR = 1 | ||||
| CE | β13 = 20 | β13 = 16 | λM = 0.7 | β13 = 1, 5 | |
| λF = 0.1 | κ1 = 1 | ||||
| λM = 0.1, 0.3 | λM = 0.9 | ||||
| ST | β13 = 20 | β11 = 150 | κ2 = 1 | β13 = 50 | β13 = 1,5 |
| κ1 = 1 | β13 = 15 | λM = 0.7 | |||
| λF = 0.1 | λF = 0.3 | μDN = 0.01 | λR = 1 | λM = 0.9 | |
| λM = 0.1, 0.3 | |||||
| SA | β13 = 15,20 | β11 = 150 | β11 = 125 | β11 = 75 | β11 = 50 |
| κ1 = 1 | μDN = 0.01 | κ1 = 5 | κ1 = 20 | β13 = 1,5 | |
| λF = 0.1, 0.3 | κ2 = 20 | κ2 = 5 | κ2 = 1 | ||
| λM = 0.1, 0.3 | λR = 9 | λF = 0.7 | λF = 0.9 | ||
| μDN = 0.09 | λM = 0.7, 0.9 | ||||
| λR = 1 | |||||
| M | β13 = 20 | λF = 0.3 | β11 = 150 | β11 = 50 | β13 = 1 |
| (DAMPs) | λF = 0.1 | β13 = 15 | β13 = 5 | ||
| λM = 0.1, 0.3 | κ1 = 1,5 | λF = 0.9 | λM = 0.9 | ||
| μDN = 0.01 | λM = 0.7 | ||||
| F (PIC) | β13 = 20 | β11 = 150 | λF = 0.3 | β11 = 50 | β13 = 1,5 |
| λF = 0.1 | β13 = 15 | μDN = 0.01 | λM = 0.7 | λM = 0.9 | |
| λM = 0.1, 0.3 | κ1 = 1 | λR = 1 | |||
| P (EPO) | β13 = 15,20 | λF = 0.3 | β11 = 150 | β11 = 50 | β13 = 1, 5 |
| λF = 0.1 | κ2 = 1 | λR = 9 | |||
| λM = 0.1, 0.3 | μDN = 0.01 | λR = 3 | μDN = 0.09 | λM = 0.7, 0.9 | |
| λR = 1 | |||||
| R (ROS) | β13 = 20 | β11 = 150 | κ2 = 1 | β11 = 50 | β13 = 1,5 |
| κ1 = 1 | β13 = 15 | μDN = 0.09 | λM = 0.7 | λM = 0.9 | |
| λF = 0.1 | λF = 0.3 | λR = 1 | |||
| λF = 0.1, 0.3 |
The relative effects the perturbations have on the variable values are divided into five categories: EP, extremely positive effect (over 100% relative increase); HP, highly positive effect (50–100% relative increase); MP, moderately positive (30–50% relative increase); MN, moderately negative (30–50% relative decrease); HN, highly negative (50–100% relative decrease).