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. 2016 Sep 22;8(10):269. doi: 10.3390/toxins8100269

Figure 7.

Figure 7

Effects of bvPLA2 on the histopathological changes in the lung tissue of OVA challenged mice. (a) To observe the infiltration of inflammatory cells, the lung tissues were stained with H and E (magnification 200×); (b) the lung inflammation severity was scored by a five-point scoring system; (c) lung tissues were stained with PAS (magnification 400×) as described in the Material and Methods. The black arrows indicate goblet cells; and (d) the percentage of goblet cells per bronchiole. Normal control mice were treated with PBS alone (NC), OVA-challenged mice were treated with PBS (OVA), and OVA-challenged mice were treated with 10 µg/kg bvPLA2 (OVA+PLA2 (10 µg/kg)). The statistical analyses were conducted by one-way ANOVA followed by Newman-Keuls multiple comparison test (*** p < 0.001 vs. NC group, ## p < 0.01 and # p < 0.05 vs. OVA+PLA2 10 µg/kg group; n = 5).