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. 2016 Oct 13;8(10):296. doi: 10.3390/toxins8100296

Figure 2.

Figure 2

Structure and binding pocket of RTA-C6-P2 complex. (a) Overall structure of RTA-C6-P2 complex. The α-helixes, β-sheets and loops of RTA are colored in cyan, magenta and light pink, respectively. Hexameric peptide of P2 ribbon is shown in yellow; (b) The binding pocket of C6-P2 peptide. The binding residues are shown as sticks in the same color corresponding to the secondary elements they belong to. The residues of C6-P2 are shown as yellow sticks. The hydrogen bond is indicated by dashed lines; (c) 2Fo-Fc electron density map of the P2 peptide at the binding pocket of RTA. The density map is presented as a blue mesh at 1.5 σ level; (d) Ligplot analysis of the interactions between RTA and peptide C6-P2.