Table 3.
Serum cytokine levels among rural women (n = 201).
| Cytokines | Distribution of Detected Values Median (Interquartile Range) in pg/mL | Limit of Detection (pg/mL) | Proportion Detected n (%) | ||||
|---|---|---|---|---|---|---|---|
| Farm Dwellers | Town Dwellers | Overall | Farm Dwellers | Town Dwellers | Overall | ||
| Th2 cytokines | |||||||
| IL-4 | 4.68 (3.20–6.92) | 5.09 (3.52–8.12) | 4.84 (3.52–7.25) | 0.10 | 51 (43) | 30 (37) | 81 (40) |
| IL-5 | 2.06 (1.66–2.31) | 2.23 (1.82–3.16) | 2.07 (1.68–2.60) | 0.10 | 23 (19) | 13 (16) | 36 (18) |
| IL-13 | 4.80 (2.98–6.37) * | 6.06 (4.90–7.58) | 5.55 (3.39–7.23) | 0.10 | 39 (33) | 28 (34) | 67 (33) |
| Any Th2 cytokine | N/A | N/A | 61 (51) | 44 (54) | 105 (52) | ||
| Non-Th2 cytokines | |||||||
| IL-6 | 5.16 (3.61–7.50) | 5.27 (3.75–10.26) | 5.16 (3.62–8.69) | 0.14 | 63 (53) | 38 (46) | 101 (50) |
| IL-8 | 16.49 (10.56–36.22) | 19.47 (13.08–37.30) | 18.93 (11.45–36.90) | 0.10 | 85 (71) | 57 (70) | 142 (71) |
| IL-10 | 4.47 (2.80–5.60) | 4.22 (2.74–6.36) | 4.39 (2.77–5.87) | 0.20 | 45 (38) | 26 (32) | 71 (35) |
| IL-17 | 10.34 (6.20–15.61) | 9.13 (7.09–19.02) | 9.76 (6.40–16.10) | 0.22 | 52 (44) | 28 (34) | 80 (40) |
| IFN-γ | 10.53 (7.41–17.80) | 9.14 (6.56–17.30) | 10.30 (7.41–17.30) | 0.10 | 60 (50) | 31 (38) | 91 (45) |
| Any non-Th2 cytokine | N/A | N/A | 85 (71) | 57 (70) | 142 (71) | ||
IL: interleukin; IFN- γ: interferon gamma; * p-value < 0.05; Any Th2: any Th2 cytokines (IL-4, IL-5, or IL-13) detected; Any non-Th2: Any non-Th2 cytokines (IL-6, IL-8, IL-17, IL-10, or IFN-γ) detected; N/A: Not applicable.