Table 4.
Host-Related Factors | Asthma-Related Outcomes: Odds Ratio (95% Confidence Interval) | |||||
---|---|---|---|---|---|---|
Doctor Diagnosed Asthma | Adult Onset Asthma | Current Asthma | FeNO > 50 ppb | Any Th2 Cytokine Detected | Any Non-Th2 Cytokine Detected | |
Prevalence (%) (n = 211) | 11% | 9% | 6% | 7% | 52% | 71% |
Age (years) | 1.01 (0.98–1.05) | 1.02 (0.99–1.06) | 1.04 (0.99–1.09) | 0.99 (0.95–1.04) | 1.00 (0.97–1.02) | 1.00 (0.97–1.02) |
BMI (kg/m2) | 1.02 (0.96–1.08) | 1.03 (0.97–1.10) | 1.01 (0.93–1.10) | 1.02 (0.95–1.10) | 1.01 (1.00–1.05) | 1.02 (0.98–1.07) |
Education (years of schooling) | 0.85 (0.74–0.96) | 0.85 (0.74–0.97) | 0.78 (0.66–0.92) | 1.18 (0.96–1.46) | 0.98 (0.89–1.07) | 1.02 (0.93–1.13) |
Born on a farm | 0.61 (0.25–1.50) | 0.67 (0.25–1.79) | 0.10 (0.01–0.79) | 0.27 (0.07–0.99) | 1.07 (0.62–1.87) | 1.17 (0.63–2.15) |
Current smoker | 1.66 (0.68–4.02) | 1.43 (0.55–3.72) | 1.44 (0.44–4.70) | 0.23 (0.06–0.84) | 0.68 (0.39–1.19) | 0.77 (0.42–1.41) |
Currently employed | 0.86 (0.36–2.07) | 0.73 (0.28–1.87) | 0.46 (0.14–1.50) | 0.55 (0.19–1.58) | 0.90 (0.51–1.59) | 1.36 (0.74–2.53) |
Atopy (positive Phadiatop) | 3.37 (1.32–8.58) | 3.10 (1.13–8.5) | 7.12 (1.52–33.40) | 21.28 (2.74–165.23) | 1.09 (0.62–1.90) | 1.32 (0.71–2.45) |
Farm vs. town dwellers | 0.65 (0.27–1.55) | 0.64 (0.25–1.65) | 0.35 (0.10–1.20) | 0.61 (0.21–1.76) | 0.91 (0.52–1.60) | 1.10 (0.59–2.03) |
Each odds ratio represents a separate unadjusted logistic regression model; Any Th2: any Th2 cytokines (IL-4, IL-5, or IL-13) detected; Any non-Th2: Any non-Th2 cytokines (IL-6, IL-8, IL-17, IL-10, or IFN-γ) detected. BMI: body mass index; FeNO: fractional exhaled nitric oxide.