Table 2.
Association of SNP genotypes with ischemic stroke (IS) susceptibility.
| Genotype | Control (n = 303) | Cases (n = 320) | OR (95% CI) | p Value |
|---|---|---|---|---|
| rs25487 | ||||
| GG | 182 (60.1%) | 212 (66.2%) | 1.00 | |
| AG | 101 (33.3%) | 102 (31.9%) | 0.61 (0.41–0.92) | 0.018 |
| AA | 20 (6.6%) | 6 (1.9%) | 0.16 (0.05–0.49) | 0.002 |
| Dominant | 0.53 (0.36–0.79) | 0.002 | ||
| Additive | 0.52 (0.37–0.74) | <0.001 | ||
| rs12645561 | ||||
| CC | 162 (53.4%) | 163 (50.9%) | 1.00 | |
| CT | 122 (40.3%) | 124 (38.8%) | 0.97 (0.66–1.44) | 0.898 |
| TT | 19 (6.3%) | 33 (10.3%) | 1.72 (0.85–3.49) | 0.132 |
| Dominant | 1.07 (0.74–1.55) | 0.707 | ||
| Additive | 1.15 (0.87–1.54) | 0.328 | ||
| rs4462560 | ||||
| CC | 88 (29.0%) | 96 (30.0%) | 1.00 | |
| CG | 160 (52.8%) | 155 (48.4%) | 0.76 (0.49–1.16) | 0.196 |
| GG | 55 (18.2%) | 69 (21.6%) | 1.10 (0.64–1.89) | 0.717 |
| Dominant | 0.84 (0.56–1.25) | 0.395 | ||
| Additive | 1.01(0.78–1.32) | 0.925 |
Logistic regression analyses adjusted for age, sex, smoking, drinking, diabetes, hypertension, total cholesterol.