Table 3.
(a) SNPs Associated with IS Severity | ||||
Genotype | Mild (n = 228) | Severe (n = 92) | OR (95% CI) | p Value |
rs25487 | ||||
GG | 143 (62.7%) | 69 (75.0%) | 1.00 | |
AG | 81 (35.5%) | 21 (22.8%) | 0.54 (0.31–0.95) | 0.033 |
AA | 4 (1.8%) | 2 (2.2%) | 1.12 (0.19–6.50) | 0.897 |
Dominant | 0.57 (0.33–0.98) | 0.043 | ||
Additive | 0.63 (0.38–1.05) | 0.076 | ||
(b) SNPs Associated with IS Short-Term Recovery | ||||
Genotype | Improvement (n = 174) | No Change/Deterioration (n = 146) | OR (95% CI) | p Value |
rs25487 | ||||
GG | 105 (60.3%) | 107 (73.3%) | 1.00 | |
AG | 65 (37.4%) | 37 (25.3%) | 0.57 (0.35–0.94) | 0.026 |
AA | 4 (2.3%) | 2 (1.4%) | 0.53 (0.09–3.00) | 0.470 |
Dominant | 0.57 (0.35–0.92) | 0.022 | ||
Additive | 0.60 (0.38–0.94) | 0.026 |
Logistic regression analyses adjusted for age, sex.