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. 2016 Oct 17;13(10):1016. doi: 10.3390/ijerph13101016

Table 3.

Association of XRCC1 rs25487 polymorphism with IS severity and short-term recovery.

(a) SNPs Associated with IS Severity
Genotype Mild (n = 228) Severe (n = 92) OR (95% CI) p Value
rs25487
GG 143 (62.7%) 69 (75.0%) 1.00
AG 81 (35.5%) 21 (22.8%) 0.54 (0.31–0.95) 0.033
AA 4 (1.8%) 2 (2.2%) 1.12 (0.19–6.50) 0.897
Dominant 0.57 (0.33–0.98) 0.043
Additive 0.63 (0.38–1.05) 0.076
(b) SNPs Associated with IS Short-Term Recovery
Genotype Improvement (n = 174) No Change/Deterioration (n = 146) OR (95% CI) p Value
rs25487
GG 105 (60.3%) 107 (73.3%) 1.00
AG 65 (37.4%) 37 (25.3%) 0.57 (0.35–0.94) 0.026
AA 4 (2.3%) 2 (1.4%) 0.53 (0.09–3.00) 0.470
Dominant 0.57 (0.35–0.92) 0.022
Additive 0.60 (0.38–0.94) 0.026

Logistic regression analyses adjusted for age, sex.