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. 2016 Oct 31;3(5):ENEURO.0230-16.2016. doi: 10.1523/ENEURO.0230-16.2016

Figure 8.

Figure 8.

The absence of Lhx2 and the absence of Emx2 have distinctly different effects on Olfr15 expression frequency. A, In situ hybridization image showing normal Olfr15 expression in the ventral region of the olfactory epithelium in a littermate control. B, When Lhx2 is deleted in OSNs, Olfr15 expression frequency decreases. C, An image of the left half of a more caudal section from a littermate control shows the normal expression of Olfr15 in the ventral olfactory epithelium. This image shows one of the rare instances of the misexpression of Olfr15 in the dorsal olfactory epithelium in control genotypes (arrow). D, When both Lhx2 and Emx2 are deleted, Olfr15 expression frequency decreases in the ventral region, where it is normally expressed, but misexpression increases in the dorsal region. The approximate boundaries between dorsal and ventral olfactory epithelium are marked in C and D. NC, Air space of the nasal cavity; S, nasal septum; T, turbinate. Scale bars, 100 µm.