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. 2016 Sep 22;21(10):1268. doi: 10.3390/molecules21101268

Table 2.

Scope of palladium-catalyzed C–H arylation of triazoles.

graphic file with name molecules-21-01268-i002.jpg

Entry Ar1 Ar2 R Yield
1 4-pyridyl phenyl H 89%
2 4-pyridyl 4-MeO-phenyl H 85%
3 4-pyridyl 4-EtO2C-phenyl H 92%
4 4-pyridyl 4-F3C-phenyl H 83%
5 4-pyridyl 4-NC-phenyl H 79%
6 4-pyridyl 4-F-phenyl H 51%
7 4-pyridyl 3-Me-phenyl H 86%
8 4-pyridyl 3-OHC-phenyl H 32%
9 4-pyridyl 2-MeO-phenyl H 82%
10 4-pyridyl 2-Me-phenyl H 49%
11 4-pyridyl 1-naphthyl H 78%
12 4-pyridyl phenyl H 80%
13 4-pyridyl phenyl H 84%
14 phenyl phenyl H 80%
15 4-MeO-phenyll phenyl H 64%
16 2-F3C-phenyl phenyl H 50%
17 4-pyridyl phenyl Me 20% a
18 4-pyridyl phenyl Et 8% a

a Microwave heating, 140 °C, 15 min.