Figure 2. Inhibition of DYRK1A affects the colony forming ability of the HNSCC cells.
(a) Colony formation assay following siRNA mediated knockdown of DYRK1A or control siRNA in a panel of HNSCC cell lines, as indicated. Colonies formed were visualized after staining with methylene blue. (b) A graphical representation of the colony forming ability of the HNSCC cells upon DYRK1A silencing (*p < 0.05). (c) Colony forming ability of the HNSCC cells upon inhibition of DYRK1A using harmine or control (DMSO), in the indicated panel of HNSCC cells. (d) A graphical representation of the colony forming ability of HNSCC cells upon harmine treatment (*p < 0.05). Representative images were photographed at a magnification (2.5x).