Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Adjuvant alone does not induce germinal center responses. (A) C57BL/6 mice were immunized with 0.2 μg ISCOMs alone or with 10 μg BG505 SOSIP trimers and 0.2 μg ISCOMs at weeks 0, 6, and 20. Germinal center responses in draining lymph nodes were analyzed at week 22. (B) Flow plots and (C) graphs of GC Tfh cells (CXCR5+PD-1hi), Tfh cells (CXCR5+BTLAhi), and germinal center B cells (FAShiGL7hi) in draining lymph nodes of mice immunized with adjuvant alone or with trimer and adjuvant.
