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A model of the proposed T. cruzi large subunit rRNAs assembly pathway. (A) 5.8S, LSU-α, and LSU-β form a scaffold. The gray color indicates the outline of the completely assembled large subunit. (B) srRNA2, -3, and ES7L are assembled. (C) srRNA4 and srRNA1 are assembled next. (D) 5S rRNA, ES42L, ES31L, and the KSD properly assemble to complete the large subunit. (E) Color key for the eight pieces of rRNA.
