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. 2016 Oct 10;113(43):12256–12261. doi: 10.1073/pnas.1609695113

Fig. S3.

Fig. S3.

The intronic PASs activated by ICP27 are within a short distance of the TSS and the affected 5′ splice site. (A and C) The distributions of the distance from activated PASs in intron 1 (n = 132), or in intron 2 or downstream of retained intron 1 (n = 16) to the TSS are graphed in A and C. The mean distance from TSS to PAS for the 132 genes with activated PASs in intron 1, and in the 16 genes with activated PASs in intron 2 or downstream of exon 2 was 1,672 bp with 95% CI [1,512 bp, 1,834 bp] and 1,601 bp with 95% CI [1,273 bp, 1,931 bp], respectively. (B and D) The distributions of the distance from activated PASs in intron 1 (n = 132), or in intron 2 or downstream of exon 2 (n = 16) to affected 5′ splice sites are shown in B and D, respectively. The mean distance from TSS to PAS for activated PASs in intron 1, and in intron 2 or downstream of exon 2 was 1,338 bp with 95% CI [1,177 bp, 1,498 bp] and 856 bp with 95% CI [597 bp, 1,143 bp], respectively.