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SHU-9119 treatment in OffOb rats. ICV infusion of Mc3/4r antagonist [SHU9119 (1 nmol⋅h−1)] in juvenile (1-mo-old) male and female OffOb and OffCon rats. BW (A and B) and FI (C and D) are shown (n = 6). *P < 0.001 and †P < 0.05 vs. OffCon using the Student t test. Means not sharing the same letter are significantly different from each other (P < 0.05) by generalized least squares (GLS) regression analysis.
