Fig. S3.

(A) Injection (i.p.) of Mc3/4r agonist (MTII, 2 mg/kg) in adult (12-mo-old) male offspring at 1300 hours. MAP (B and C) and HR (D and E) responses to MTII change in BW (F) and FI (G) over the following 24 h are shown. BPM, beats per minute. Data are expressed as the hourly average of MAP and HR per group (n = 5–6; mean ± SEM). **P < 0.01 vs. OffCon using the Student t test. ^#P < 0.001, vs. OffCon, repeated measured ANOVA, followed by Tukey post hoc test. Means not sharing the same letter are significantly different from each other (P < 0.05) by generalized least squares (GLS) regression analysis.