Fig. S7.
Enhanced RSNA, RAS, and oxidative stress in OffOb and NL male and female mice. Cortical mRNA expression of TH (A, B, K, and L), renin (C, D, M, and N), AT1a (E, F, O, and P), and Nox-4 (G, H, Q, and R; NAPDH oxidase) (n = 5–8) and serum TBARS (micromolar) concentration (I, J, S, and T) (n = 5) in OffOb-WT, -Mc4rKO, and -Mc4rPVH mice and in NL-WT, -Mc4rKO, and -Mc4rPVH mice. Data are presented as the average concentration or normalized value to the GeNorm program values of β-actin and TATAbox. Means not sharing the same letter are significantly different from each other (P < 0.05) by generalized least squares (GLS) regression analysis.