Table 3. EML4-ALK fusions detected in this study.
| Alternate name | EML4 spliced exon | Breakpoint variety (bp)* | ALK spliced exon |
|---|---|---|---|
| EML4-ALK variant 1 | 13 | −/−/ins69/−/−/− | 20 |
| EML4-ALK variant 3a/b | 6 | −/−/ins33/− | 20 |
| EML4-ALK variant 2 | 20 | −/−/ins18/− | 20 |
| EML4-ALK variant 4 | 15 | del71 | 20 |
| EML4-ALK variant 4′ | 14 | ins11del49/del12/del36 | 20 |
| EML4-ALK variant 5′ | 18 | — | 20 |
| EML4-ALK variant 5a/b | 2 | −/ins117 | 20 |
| / | 17 | ins68 | 20 |
*Differing breakpoints result in different cDNA isoforms: ins indicates insertion, and del indicates deletion.