Table 2.
Influence of the applied alpha-beta ratio on the findings for odds ratios, VX and DX%
| Toxicity type | Findings for α/β = 5.4 Gy compared to α/β = 3 Gya |
|---|---|
| Rectal bleeding | Similar trends |
| Stool frequency | Similar trends |
| Diarrhoea | Odds ratios not significant for α/β = 5.4 Gy |
| Completeness of evacuation | No significance for α/β = 3 Gy or α/β = 5.4 Gy |
| Anorectal pain | Similar trends |
| Urgency/tenesmus | Similar trends |
| Proctitis | Similar trends |
Abbreviations: V X percentage of the rectal volume receiving at least X EQD2 Gy after applying an α/β = 3 or 5.4 Gy, D X% minimum EQD2 Gy dose to the most irradiated X percentage of rectal volume after applying an α/β = 3 or 5.4 Gy, EQD2 Gy equivalent dose in 2-Gy fractions using α/β = 3 or 5.4 Gy, α/β alpha-beta ratio
aIndication of whether significance still exists when an α/β of 5.4 Gy is used instead of 3 Gy