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. 2016 Oct 31;20:34. doi: 10.1186/s40824-016-0081-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — Advantage and application of different lipids-surface engineering on PLGA nanoparticles. The bare PLGA nanoparticles have major drawbacks such as hydrophobic surface, rapid phagocytic clearance and initial burst release. Cell membrane derived lipid vesicles or synthetic lipids based surface engineering on PLGA nanoparticles prevent the fore told drawbacks and improve the clinical performance