Table 2.
Sample demographic data according to S. aureus antimicrobial resistance
| Demographic data | All patients | Gentamicin* | Neomycin** | Fusidic acid** | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| n=91 | R (n=10) | S (n=58) | p | R (n=29) | S (n=39) | p | R (n=4) | S (n=64) | p | |||
| Male Sex – n(%) | 48 (52,7) | 5 (50,0) | 33 (56,9) | 0,740‡ | 15 (51,7) | 23 (59,0) | 0,625¶ | 2 (50,0) | 36 (56,3) | 1,000‡ | ||
| Age (years) | 0,674§ | 0,312§ | 0,900§ | |||||||||
| Range | 0,3 -30 | |||||||||||
| Mean ± SD | 7,0±5,2 | 6,6±2,2 | 7,4±5,9 | 8,1±5,9 | 6,7±5,3 | 7,0±3,8 | 7,4±5,7 | |||||
| Median (IQR) | 6,0 | 7,0 | 6,0 | 7,0 | 6,0 | 8,0 | 6,5 | |||||
| (2,6-10,0) | (0,5-10,0) | (0,5-30,0) | (0,5-30,0) | (0,6-26,0) | (2,0-10,0) | (0,5-30,0) | ||||||
| Topical antibiotic use – n(%) | 9,0 (9,9) | 0 (0,0) | 8 (13,8) | 0,593‡ | 3 (10,3) | 5 (12,8) | 1,000‡ | 0 (0,0) | 8 (12,5) | 0,975‡ | ||
| Previous skin infection – n(%) | 30 (33,0) | 4 (40,0) | 20 (34,5) | 0,733‡ | 12 (41,4) | 12 (30,8) | 0,516¶ | 0 (0,0) | 24 (37,5) | 0,289‡ | ||
| Recurrent infections– n(%) | 24 (26,4) | 3 (30,0) | 16 (27,6) | 1,000‡ | 10 (34,5) | 9 (23,1) | 0,445¶ | 0 (0,0) | 19 (29,7) | 0,570‡ | ||
| Systemic antibiotic use – n(%) | 27 (29,7) | 2 (20,0) | 19 (32,8) | 0,250‡ | 9 (31,0) | 12 (30,8) | 1,000 | 2 (50,0) | 19 (29,7) | 0,658‡ | ||
| Hospitalization | – n(%) 7 (7,7) | 1 (10,0) | 5 (8,6) | 1,000‡ | 2 (6,9) | 4 (10,3) | 1,000‡ | 1 (25,0) | 5 (7,8) | 0,315‡ | ||
| Disease duration (years) £ | 0,896§ | 0,121§ | 0,444§ | |||||||||
| range | (0,1–30,0) | |||||||||||
| mean ± SD | 4,7 ± 4,7 | 5,2±2,7 | 4,9±5,4 | 6,1±6,2 | 4,1±3,8 | 6,8±4,0 | 4,8±5,1 | |||||
| median (IQR) | 3,0 | 5,6 | 3,0 | 5,0 | 2,5 | 8,0 | 4,0 | |||||
| (1,5 – 6,3) | (0,5-10,0) | (0,3-30,0) | (0,3-30,0) | (0,3-1,7) | (1,5-10,0) | (0,3-30,0) | ||||||
| EASI score £ | 0,965§ | 0,437§ | 0,009§ | |||||||||
| range | (0,4–40,5) | |||||||||||
| mean ± SD | 7,8 ± 8,1 | 9,1±11,3 | 9,0±8,3 | 9,9±8,1 | 8,3±9,2 | 20,5±17,1 | 8,3±7,6 | |||||
| median (IQR) | 5,4 | 5,7 | 6,2 | 7,3 | 4,9 | 17,8 | 5,7 | |||||
| (2,0 – 9,9) | (1,2-40,5) | (0,6-32,2) | (0,6-32,2) | (0,6-40,5) | (6,0-40,5) | (0,6-32,2) | ||||||
§
Mann Whitney Test;
¶
Pearson's Chi-square Test with continuity correction;
‡
Fisher's Exact Test; £ asymmetric variable;
*
defined by disk diffusion technique;
**
defined by MIC breakpoints. R: resistant; S: sensible; SD: standard deviation; IQR: interquartile range (the values between the 75th percentile and the 25th percentile).