Chart 1.

Criteria proposed for the diagnosis of antisynthetase syndrome³

Diagnosis: Presence of one antisynthetase antibody plus two major criteria or one higher criterion and two minor criteria.
Major criteria:
1. Interstitial lung disease (not explained by environmental, occupational, medication exposure, and not related to any other base disease)
2. Polymyositis or dermatomyositis according to criteria set forth by Bohan & Peter
Minor criteria:
1. Arthritis
2. Raynaud phenomenon
3. Mechanic's hand