Skip to main content
. Author manuscript; available in PMC: 2016 Oct 31.
Published in final edited form as: Cell Metab. 2014 Mar 4;19(3):418–430. doi: 10.1016/j.cmet.2014.02.009

Figure 4. The Effects of Macronutrient Balance on Mitochondrial Function in the Liver.

Figure 4

(A) Response surfaces showing the effect of dietary macronutrients on mitochondrial state IVo respiration with pyruvate as substrate (pmol O2 consumed/min/U of citrate synthase) in the liver at 15 months. Surfaces are shown for diet-based data (top), intake-based data (middle), and intake-based data adjusted to lean body mass (bottom). The highest activity is indicated in red (low-protein diets), and the lowest is indicated in blue.

(B) Response surfaces showing the effect of dietary macronutrients on mitochondrial state IVo respiration with palmitoyl carnitine as substrate (pmol O2 consumed/min/U of citrate synthase) in the liver at 15 months. Surfaces are shown for diet-based data (top), intake-based data (middle), and intake-based data adjusted to lean body mass (bottom). The highest activity is indicated in red (high-fat diets), and the lowest is indicated in blue. See also Figure S4 and Tables S6 and S7.