Table 2.
Tumor/Serum ratio of concentrations of hamster IgG after I.T. injection of either J43 (BioXcell) or WR-mAb1. If one of the concentrations was below the LOQ, LOQ was used to calculate the ratio which appears in the table labeled with *. (NA: not applicable, ND: not detected, i.e., both concentrations in tumor and serum were below LOQ).
Day post-injection | ||||||
---|---|---|---|---|---|---|
Models |
treatments |
1 |
3 |
5 |
7 |
11 |
B16F10 | J43 | 0.6 | NA | 0.2 | NA | 3* |
WR-mAb1 | 31 | NA | 4 | NA | 605* | |
MCA 205 | J43 | 0.2 | 0.1 | 0.1 | 4* | ND |
WR-mAb1 | 8 | 13 | 51 | 84* | 132* |