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irAEs by Grade
| irAEs | Grade 1 | Grade 2 | Grade 3 | Grade 4 | Grade 5 | Total |
|---|---|---|---|---|---|---|
| Hepatotoxicity | 135 | 23 | 32 | 7 | 0 | 197 |
| Dermatitis | 69 | 36 | 18 | 0 | 0 | 123 |
| Diarrhea | 25 | 20 | 29 | 12 | 1 | 87 |
| Hypophysitis | 1 | 6 | 10 | 0 | 0 | 17 |
| Uveitis | 1 | 5 | 1 | 1 | 0 | 8 |
| Other | 1 | 6 | 8 | 0 | 0 | 15 |
| Total* | 232 | 96 | 98 | 20 | 1 | 447 |
Abbreviation: irAEs, immune-related adverse events.
Patients could have experienced more than one irAE. Therefore, the total number of irAEs is more than the total number of patients.
