Table 1.
Non-histone targets of HATs and HDACs
| Non-histone | HAT | HDAC |
|---|---|---|
| p53 | p300/CBP46, 47 | HDAC148, SIRT149 |
| YY1 | p300/CBP50 | HDAC251 |
| STAT3 | p300/CBP17 | HDAC317 |
| HMG | CBP, PCAF52 | NA |
| c-Myc | PCAF/GCN5, TIP6053 | NA |
| AR | p300/CBP, TIP6054 | HDAC155 |
| ER | p30056 | NA |
| GATA | CBP (GATA1)57, p300 and PCAF (GATA2)58 | HDAC3(GATA2)59 |
| EKLF | p300/CBP60 | NA |
| MyoD | PCAF, CBP, and p30061, 62 | HDAC163 |
| E2F/Rb | PCAF, CBP, and p30064 | HDAC165 |
| NF-kB | p300/CBP66 | HDAC366, SIRT167 |
| HIF1α | ARD168 | HDAC469 |
| Smad7 | p30070 | |
| α-Tubulin | NA | HDAC625, SIRT223 |
| Importin-α | CBP, p30071 | NA |
| Ku70 | PCAF, CBP72 | SIRT172 |
| Hsp90 | NA | HDAC673 |
| E1A | p300, PCAF74 | NA |
| CtIP | GCN594 | HDAC394, SIRT675 |
| β-catenin | PCAF76, p30077 | SIRT178, HDAC679 |
| Survivin | NA | HDAC680 |
| FoxO1 | CBP/p30081 | SIRT182 |
| FoxO3a | CBP/p30082 | SIRT182, SIRT283, SIRT384 |
| PGC1- α | GCN585 | SIRT174, 86 |
| FXR | p30087 | SIRT188 |
NA: Not available