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. 2016 Oct 1;143(19):3514–3521. doi: 10.1242/dev.137398

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© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Fig. 2. — Effects of cyclopamine on chick wing digit patterning. Untreated wing (−Cyc) with three digits 1-2-3 (A), wings treated with cyclopamine (+Cyc) at HH20/21 with a 1-2 pattern with a bifurcated digit 2 phalanx (arrow in B; n=3/126), with a 1-2-2 pattern (C; n=4/126), with a 1-2-2-2 pattern (D; n=27/126), with a 1-2-2-3 pattern (E; n=38/126) and with normal pattern (F; n=54/126). Note, digit 2s bifurcate from a fused metacarpal in D and E. Scale bars: 1 mm.