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Shh represses the formation of a posterior digit condensation. In untreated wings, the posterior-most Sox9-expressing digit condensation regresses (indicated by an X in A) but forms either a digit 2 or 3 in wings treated with cyclopamine at HH20/21 (B). Note that resolution of distinct cartilage condensations is delayed in cyclopamine-treated wings. Scale bars: 500 μm.
