Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2016 Oct 1;143(19):3470–3480. doi: 10.1242/dev.134098

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2016. Published by The Company of Biologists Ltd

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

PMC Copyright notice

Fig. 7. — Model of ISCs in adult medaka fish. Bulging of the medaka intestinal epithelial surface creates folds and furrows. Proliferatively active intestinal epithelial stem cells are located in furrows at the base of intestinal folds. Apically adjacent, EdU⁺/pH3⁺ domain represents transit-amplifying compartment. Differentiated cells are pushed towards fold tip, where they are shed. Lgr4/5/6, axin2a, axin2b and rspo1 stem cell markers show graded expression in intestine at base of folds up to mid-base part. Sox9b expression is confined to base of folds.