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. 2016 Oct 25;9:6407–6415. doi: 10.2147/OTT.S111846

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© 2016 Yang and Shao. This work is published and licensed by Dove Medical Press Limited

The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.

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Kaplan–Meier analysis of OS, RFS, DMFS, and DFS of patients according to GPER1 mRNA expression.

Notes: No statistically significant difference was found in entire sample group (left column); in HER2-positive subgroup, GPER1-lower expressed patients have better DFS (middle column); in HER2-negative subgroup, GPER1-higher expressed patients have better DMFS and DFS (right column). Red lines stand for GPER1-higher expressed patients; black lines stand for GPER1-lower expressed patients. “HER2+” stands for HER2-overexpressed patients and “HER2−” stands for the remaining patients.

Abbreviations: DFS, disease-free survival; DMFS, distant metastasis-free survival; GPER1, G protein-coupled estrogen receptor 1; OS, overall survival; RFS, recurrence-free survival; Cum, cumulative.