. 2016 Oct 26;11:2671–2679. doi: 10.2147/COPD.S113450

Table 2.

Exercise training responses

Outcomes	All subjects (n=333)	6MWDi ≥350 m		6MWDi <350 m
Outcomes	All subjects (n=333)	∆≥30 m; Group 1 (n=125)	∆<30 m; Group 2 (n=98)	∆≥30 m; Group 3 (n=74)	∆<30 m; Group 4 (n=36)
Peripheral muscle force
ΔQF (Nm)	10 (0–22)^*	11 (0–21)^*	7 (−2–21)^*	15 (4–29)^*,^‡	7 (−2–15)^*
ΔQF (% from baseline)	10 (0–25)^*	8 (0–20)^*	5 (−2–21)^*	16 (6–46)^*,^‡	11 (−2–24)^*
Exercise capacity
ΔOxygen uptake (% from baseline)	8 (−5–21)^*	11 (−4–24)^*	2 (−6–16)^*	14 (0–24)^*,^‡	−4 (−17–0)^*,^†,^§
ΔMax workload (% from baseline)	14 (0–30)^*	16 (0–28)^*,^§	11 (0–21)^*	22 (0–50)^*,^†,^‡	0 (0–25)^†,^§
Δ6MWD (m)	43 (12–78)^*	59 (45–91)^*	0 (−26–17)^†	86 (54–136)^*,^†,^‡	−8 (−62–18)^*,^†,^§
Δ6MWD (% from baseline)	10 (3–23)^*	13 (9–21)^*	0 (−5–3)^†	39 (23–67)^*,^†,^‡	−3 (−24–6)^*,^†,^§
Health-related quality of life
ΔCRDQ dyspnea	5 (2–8)^*	6 (3–9)^*	3 (1–8)^*,^†	6 (2–8)^*	3 (0–6)^*,^†,^§
ΔCRDQ total score	15 (8–24)^*	17 (11–25)^*	12 (4–22)^*,^†	16 (11–24)^*	13 (2–22)^*

Notes: Data shown as median (IQR). Data was only analyzed for subjects with data at both baseline and 3 months. Group 1: 6MWDi ≥350 m and Δ6MWD ≥30 m; Group 2: 6MWDi ≥350 m and Δ6MWD <30 m; Group 3: 6MWDi <350 m and Δ6MWD ≥30 m; and Group 4: 6MWDi <350 m and Δ6MWD <30 m.

P<0.05 for changes from baseline.

^†

Post hoc test versus 1;

^‡

post hoc test versus 2;

^§

post hoc test versus 3.

Abbreviations: Δ, difference (3 months − baseline); 6MWD, 6-minute walk distance; 6MWDi, initial 6MWD; CRDQ, chronic respiratory disease questionnaire; IQR, interquartile range; max, maximum; QF, quadriceps force.