FIGURE 3.

Concentration-dependent effect of SOCE inhibitors on HDMEC without GPCR stimulation. A–C, changes in basal electrical resistance over time after addition of different concentrations of Gd³⁺ (A), BTP2 (B), and 2-APB (C) in the absence of stimulation with GPCR agonists are represented. The data are represented as means ± S.D. of four independent experiments (for Gd³⁺, except 1 μm Gd³⁺ condition where n = 3) and three independent experiments (for all concentrations of BTP2 and 2-APB) per condition. The typical concentrations as used in Fura-2 recordings are highlighted in red.