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. 2016 Sep 13;291(44):22894–22912. doi: 10.1074/jbc.M116.756114

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© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 5. — BTP2 effects on barrier function in response to thrombin, histamine and S1P. A–C, changes in electrical resistance after stimulation with thrombin (A), histamine (B), and S1P (C) in the presence of 1 μm (magenta), 5 μm (black), or 10 μm BTP2 (red) compared with controls (blue). The data represent means ± S.D. from four independent wells. D–F, quantification of the maximum change in normalized resistance (Δ Normalized Resistance) upon thrombin (D), histamine (E), and S1P (F) stimulation in the absence or presence of 1, 5, or 10 μm BTP2. The data are represented as means ± S.D. from 6–12 independent experiments as marked in the bar graphs.