TABLE 3.

C41C4.1 KO worms exhibit hypersensitivity to hydrogen peroxide

The number of living animals after 2 h of hydrogen peroxide treatment was determined. KO (RB813 strain) animals exhibited lower tolerance to hydrogen peroxide than N2 (wild-type) animals (N2 vs. RB813, p = 0.00017, Holm's test). KO worms harboring the wild-type C41C4.1 gene (FX18330 strain) showed a tolerance phenotype comparable with the N2 animals (N2 vs. FX18330, p = 0.876; FX18330 vs. RB813, p = 0.00112, Holm's test).

H2O2 treatment	N2 (n = 131)	RB813 (n = 124)	FX18330 (n = 63)	p value
	% survival rate
2 h	60.3	34.7	61.9	3.04 × 10−5