Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Meta-analysis for the safety outcomes (continuous data)
| Outcome | Studies (n) | Participants analyzed (n)
|
WMD (95% CI) | I2 (%) | P-value | |
|---|---|---|---|---|---|---|
| Levomilnacipran | Placebo | |||||
| Pulse rate | 4 | 1,298 | 756 | 7.56 (6.81, 8.31) | 20 | <0.00001 |
| SBP | 4 | 1,300 | 756 | 3.14 (2.37, 3.90) | 0 | <0.00001 |
| DPB | 4 | 1,300 | 756 | 3.45 (2.86, 4.05) | 0 | <0.00001 |
| QTcB | 3 | 1,171 | 631 | 8.59 (6.97, 10.20) | 0 | <0.00001 |
Abbreviations: WMD, weighted mean difference; CI, confidence interval; SBP, systolic blood pressure; DPB, diastolic blood pressure.
